Metformin attenuates inflammation and boosts autophagy in the liver and intestine of chronologically aged rats

CONCLUSIONS: Metformin intervention can boost the autophagy level in the liver and intestine and reduce the expression of aging-related inflammatory factors in aged rats, and these effects may be related to the increase of the AMPK phosphorylation level.PMID:37967593 | DOI:10.1016/j.exger.2023.112331

Source: Experimental Gerontology - November 15, 2023 Category: Geriatrics Authors: Zheng Kuai Xin Chao Yuting He Weiying Ren Source Type: research