Multifactorial Dependence of Muscle Relaxant Efficacy in Lower Back Pain

We read with interest the article by Abril et  al., who reported a study on the efficacy of seven skeletal muscle relaxants (SMRs) for lower back pain (LBP) (1). Four randomized controlled trials were retrospectively pooled and analyzed together for efficacy and adverse-effect profiles of baclofen, metaxalone, tizanidine, diazepam, orphenadrin e, methocarbamol, and cyclobenzaprine compared with placebo and whether efficacy was related to age, sex, or baseline LBP-related functional impairment, as assessed by the Roland-Morris Disability Questionnaire (RMDQ) (1).
Source: The Journal of Emergency Medicine - Category: Emergency Medicine Authors: Tags: Letter to the Editor Source Type: research