TIPRL1 and its ATM-dependent phosphorylation promote radiotherapy resistance in head and neck cancer

ConclusionsOur findings underscore a clinically relevant role for TIPRL1 and its ATM-dependent phosphorylation in RT resistance through modulation of the DDR, highlighting its potential as a new HNSCC predictive marker and therapeutic target.
Source: Cellular Oncology - Category: Cancer & Oncology Source Type: research