Effectiveness of multiple disease-modifying therapies in relapsing-remitting multiple sclerosis: causal inference to emulate a multiarm randomised trial

Conclusions
The effectiveness of natalizumab and fingolimod in active RRMS is superior to dimethyl fumarate, teriflunomide, glatiramer acetate and interferon beta. This study demonstrates the utility of MSM in emulating trials to compare clinical effectiveness among multiple interventions simultaneously.

Source: Journal of Neurology, Neurosurgery and Psychiatry - November 15, 2023 Category: Neurosurgery Authors: Diouf, I., Malpas, C. B., Sharmin, S., Roos, I., Horakova, D., Kubala Havrdova, E., Patti, F., Shaygannejad, V., Ozakbas, S., Eichau, S., Onofrj, M., Lugaresi, A., Alroughani, R., Prat, A., Duquette, P., Terzi, M., Boz, C., Grand'Maison, F., Sola, P., Fer Tags: Editor's choice Multiple sclerosis Source Type: research