High-resolution PGT-A results in incidental identification of patients with small pathogenic copy number variants

ConclusionHigh-throughput high-resolution SNP array –based PGT-A has the ability to detect previously unknown and clinically significant parental deletions, duplications, and translocations. The use of cost-effective SNP array–based PGT-A methods may improve the effectiveness of PGT by identifying and preventing previously unknown pathogenic CNVs in children born to patients seeking in vitro fertilization.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research