Genetic and biological drivers of prostate cancer disparities in Black men

Nature Reviews Urology, Published online: 14 November 2023; doi:10.1038/s41585-023-00828-wGenetic and ancestral factors, molecular pathways involving androgen and non-androgen receptor signalling, inflammation, epigenetics, the tumour microenvironment and tumour metabolism are posited as biological factors that potentially contribute to racial disparities in Black men with prostate cancer.

Source: Nature Reviews Urology - November 14, 2023 Category: Urology & Nephrology Authors: Jun Gong Daniel M. Kim Michael R. Freeman Hyung Kim Leigh Ellis Bethany Smith Dan Theodorescu Edwin Posadas Robert Figlin Neil Bhowmick Stephen J. Freedland Source Type: research