On-demand Versus Continuous Maintenance Treatment With a Proton Pump Inhibitor for Mild Gastroesophageal Reflux Disease: A Prospective Randomized Multicenter Study

CONCLUSIONS: Continuous treatment seems to be more appropriate for the initial maintenance treatment of non-erosive GERD or mild erosive esophagitis than on-demand treatment. Stepping down to on-demand treatment needs to be considered after a sufficient period of continuous treatment.PMID:37814436 | PMC:PMC10577461 | DOI:10.5056/jnm23130

Source: Journal of Neurogastroenterology and Motility - October 10, 2023 Category: Gastroenterology Authors: Da Hyun Jung Young Hoon Youn Hye-Kyung Jung Seung Young Kim Cheal Wung Huh Cheol Min Shin Jung-Hwan Oh Kyu Chan Huh Moo In Park Suck Chei Choi Ki Bae Kim Seon-Young Park Joong Goo Kwon Yu Kyung Cho Jung Ho Park Jeong Eun Shin Eun Jeong Gong Jae Hak Kim Su Source Type: research