TP induces hepatic intolerance to FasL-mediated hepatocyte apoptosis by inhibiting XIAP

In conclusion, TP presensitizes hepatocytes and enhances the sensitivity of hepatocytes to the Fas/FasL pathway by inhibiting the protein expression of XIAP, leading to hepatocyte apoptosis.PMID:37944651 | DOI:10.1016/j.toxlet.2023.11.001

Source: Toxicology Letters - November 9, 2023 Category: Toxicology Authors: Xue Fan Yangping Zhu Shuang Peng Yingying Miao Qian Lu Luyong Zhang Zhenzhou Jiang Qinwei Yu Source Type: research