Docking of T6361 Analogues as Potential Inhibitors of E.coli MurA Followed by ADME-Toxicity Study

CONCLUSION: We propose two analogues of T6361 as new potential inhibitors of MurA enzyme. Their good ADME-Toxicity profile qualifies them to reach in vitro and in vivo assays as future lead molecules.PMID:37929742 | DOI:10.2174/0115701638244582231025110143

Source: Current Drug Discovery Technologies - November 6, 2023 Category: Drugs & Pharmacology Authors: Ilham Boulhissa Hanane Boucherit Abdelouahab Chikhi Abderrahmane Bensegueni Source Type: research