Investigations on Compaction Behavior of Kollidon < sup > ® < /sup > SR-Based Multi-component Directly Compressed Tablets for Preparation of Controlled Release Diclofenac Sodium

In conclusion, optimum quaternary tablets were obtained with optimum crushing strengths, relatively low Py, and moderate percentage porosities among all prepared quaternary tablets. The drug release of the optimum quaternary tablets demonstrated similar in vitro release profile compared to that of the marketed product with a mechanism of release that follows Korsmeyer-Peppas model.PMID:37945987 | DOI:10.1208/s12249-023-02685-7
Source: AAPS PharmSciTech - Category: Drugs & Pharmacology Authors: Source Type: research