An update on the use of image-derived input functions for human PET studies: new hopes or old illusions?

ConclusionImprovements in PET scanner technology and software for automated IDIF extraction may allow to solve some of the major limitations associated with IDIF, such as partial volume effects and poor temporal sampling, with the exciting potential for accurate estimation of single kinetic rates. Nevertheless, until individualized radiometabolite correction can be performed effectively, IDIF approaches remain confined at best to a few tracers.
Source: EJNMMI Research - Category: Radiology Source Type: research