A narrative review of acute pancreatitis-induced splanchnic vein thrombosis: from pathogenesis to clinical management

In this study, we reviewed the latest academic publications in APISVT, and discussed its pathogenesis, clinical presentation, adverse outcome and treatment, especially focused on the role of anticoagulant therapy. It was indicated that anticoagulation therapy can significantly elevate thrombus recanalization and reduce the incidence of complications and mortality with no increase of bleeding. Actually, as most of these studies were retrospective analyses and prospective studies included small samples, the conclusion remains controversial. Thus, well-designed randomized controlled trials are urged to verify the effectiveness and safety of anticoagulation therapy for APISVT.PMID:37933195 | DOI:10.1080/00365521.2023.2271111
Source: Scandinavian Journal of Gastroenterology - Category: Gastroenterology Authors: Source Type: research