Advanced Magnetic Resonance Imaging and Molecular Imaging of the Painful Knee

Semin Musculoskelet Radiol 2023; 27: 618-631 DOI: 10.1055/s-0043-1775741Chronic knee pain is a common condition. Causes of knee pain include trauma, inflammation, and degeneration, but in many patients the pathophysiology remains unknown. Recent developments in advanced magnetic resonance imaging (MRI) techniques and molecular imaging facilitate more in-depth research focused on the pathophysiology of chronic musculoskeletal pain and more specifically inflammation. The forthcoming new insights can help develop better targeted treatment, and some imaging techniques may even serve as imaging biomarkers for predicting and assessing treatment response in the future. This review highlights the latest developments in perfusion MRI, diffusion MRI, and molecular imaging with positron emission tomography/MRI and their application in the painful knee. The primary focus is synovial inflammation, also known as synovitis. Bone perfusion and bone metabolism are also addressed. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USAArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text

Source: Seminars in Musculoskeletal Radiology - November 7, 2023 Category: Radiology Authors: Mostert, Jacob M. Dur, Niels B.J. Li, Xiufeng Ellermann, Jutta M. Hemke, Robert Hales, Laurel Mazzoli, Valentina Kogan, Feliks Griffith, James F. Oei, Edwin H.G. van der Heijden, Rianne A. Tags: Review Article Source Type: research