Effect of High-Fat Food on the Pharmacokinetic Profile and Safety of SAF-189s, an ALK/ROS1 Inhibitor, in Healthy Chinese Adults

ConclusionsA high-fat meal had minimal effect on the pharmacokinetic profile of SAF-189s compared with a fasted state following a single dose of 160  mg. Administration with a high-fat meal led to a lower incidence of TEAEs.
Source: Drugs in R&D - Category: Drugs & Pharmacology Source Type: research