Association between the dietary antioxidant index and relative telomere length of leukocytes in the Chinese population

This study aimed to investigate the relationship between DAI and RTL. A cross-sectional study involving 1656 participants was conducted. A generalized linear regression model (GLM) and a restricted cubic spline (RCS) model were used to assess the correlation of DAI and its components with RTL. Generalized linear regression analysis revealed that DAI (β = 0.005, P = 0.002) and the intake of its constituents vitamin C (β = 0.043, P = 0.027), vitamin E (β = 0.088, P < 0.001), selenium (β = 0.075, P = 0.003), and zinc (β = 0.075, P = 0.023) were significantly and positively correlated with RTL. Gender-stratified analysis showed that DAI (β = 0.006, P = 0.005) and its constituents vitamin E (β = 0.083, P = 0.012), selenium (β = 0.093, P = 0.006), and zinc (β = 0.092, P = 0.034) were significantly and positively correlated with RTL among females. Meanwhile, among males, only vitamin E intake (β = 0.089, P = 0.013) was significantly and positively associated with RTL. RCS analysis revealed linear positive associations between DAI and its constituents' (vitamin E, selenium, and zinc) intake and RTL in the total population. Sex-stratified analysis revealed a linear positive correlation between DAI and its constituents' (vitamin E, selenium, and zinc) intake and RTL in females. Our study found a significant positive correlation between DAI and RTL, with gender differences.PMID:37926899 | DOI:10.1017/S0007114523002544
Source: The British Journal of Nutrition - Category: Nutrition Authors: Source Type: research