The Value of IgM Memory B-Cells in the Assessment of Splenic Function in Childhood Cancer Survivors at Risk for Splenic Dysfunction: A DCCSS-LATER Study

CONCLUSION: Although the number of IgM memory B-cells differed between splenectomized CCS and CCS who received radiotherapy involving the spleen or TBI, only two CCS showed abnormal values. Therefore, this assessment cannot be used to screen for splenic dysfunction.PMID:37901347 | PMC:PMC10611543 | DOI:10.1155/2023/5863995

Source: Journal of Immunology Research - October 30, 2023 Category: Allergy & Immunology Authors: Bente M Houtman Iris Walraven Elke de Grouw Richard W M van der Maazen Leontien C M Kremer Eline van Dulmen-den Broeder Marry M van den Heuvel-Eibrink Wim J E Tissing Dorine Bresters Helena J H van der Pal Andrica C H de Vries Marloes Louwerens Margriet v Source Type: research