Cardiac surgery-Associated acute kidney injury - A narrative review

Perfusion. 2023 Oct 31:2676591231211503. doi: 10.1177/02676591231211503. Online ahead of print.ABSTRACTCardiac Surgery-Associated Acute Kidney Injury (CSA-AKI) is a serious complication seen in approximately 20-30% of cardiac surgery patients. The underlying pathophysiology is complex, often involving both patient- and procedure related risk factors. In contrast to AKI occurring after other types of major surgery, the use of cardiopulmonary bypass comprises both additional advantages and challenges, including non-pulsatile flow, targeted blood flow and pressure as well as the ability to manipulate central venous pressure (congestion). With an increasing focus on the impact of CSA-AKI on both short and long-term mortality, early identification and management of high-risk patients for CSA-AKI has evolved. The present narrative review gives an up-to-date summary on definition, diagnosis, underlying pathophysiology, monitoring and implications of CSA-AKI, including potential preventive interventions. The review will provide the reader with an in-depth understanding of how to identify, support and provide a more personalized and tailored perioperative management to avoid development of CSA-AKI.PMID:37905794 | DOI:10.1177/02676591231211503

Source: Perfusion - October 31, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Sebastian Buhl Rasmussen Yuliya Boyko Marco Ranucci Filip de Somer Hanne Berg Ravn Source Type: research