71. Integrated genomic analysis of hepatocellular carcinoma using WES and aCGH

A retrospective study was conducted on a case series of hepatocellular carcinoma (HCC) using whole exome sequencing (WES) and array comparative genomic hybridization (aCGH) to evaluate genetic defects for underlying mechanisms and clinicopathologic associations. Paired DNA samples from tumor and adjacent nontumor tissues of 36 HCC cases and their clinicopathologic findings based on Edmondson-Steiner (E-S) grading, Barcelona-Clinic Liver Cancer (BCLC) stages, recurrence, and survival status were collected.
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Source Type: research