99. Donor-derived follicular lymphoma after kidney transplantation - a case report

Cancer incidence is increased in solid organ transplant recipients compared to the general population, including post-transplant lymphoproliferative disorders (PTLD). Here, we present an unusual case of a kidney transplant recipient who developed follicular lymphoma (FL) 12 years post-transplant at 39 years of age, shortly after the patient's donor father also had developed FL at 60 years of age. These coincidental diagnoses motivated evaluation of the relatedness of these two cases of FL. Traditional FISH revealed the presence of a Y chromosome in the daughter's tumor.
Source: Cancer Genetics and Cytogenetics - Category: Genetics & Stem Cells Authors: Source Type: research