ACE I/D gene polymorphisms and polycystic ovary syndrome manifestations

ConclusionThis study indicate that although ACE I/D variants frequency in PCOS women is similar to non-PCOS women, it may be involved in the pathogenesis of the disease through mechanisms regulating steroidogenesis in the ovary and suggests that ACE might be related to exacerbated clinical manifestations of PCOS which requires further investigations.
Source: Journal of Diabetes and Metabolic Disorders - Category: Endocrinology Source Type: research