Osteopontin modulates microglial activation states and attenuates inflammatory responses after subarachnoid hemorrhage in rats

CONCLUSION: OPN attenuates inflammatory responses after SAH by promoting an anti-inflammatory microglial state, potentially mediated through the integrin-FAK-STAT3 and NF-κB signaling pathways.PMID:37884185 | DOI:10.1016/j.expneurol.2023.114585

Source: Experimental Neurology - October 26, 2023 Category: Neurology Authors: Chengmei Sun Muhammad Saif Ur Rahman Budbazar Enkhjargal Jianhua Peng Keren Zhou Zhiyi Xie Lingyun Wu Tongyu Zhang Qiquan Zhu Jiping Tang Yujia Zeng John H Zhang Shanshan Xu Source Type: research