A comprehensive prognostic score for head and neck squamous cancer driver genes and phenotype traits

ConclusionThe APMHO score combining transcriptional and clinical variables showed good prognostic ability for HNSCC overall survival outcomes and was associated with different patterns of phenotypical features, immune and mutational landscape, and immunotherapy sensitivity marker expression. Future studies should validate this score in independent clinical cohorts.
Source: Hormones and Cancer - Category: Cancer & Oncology Source Type: research