Polydatin alleviates mycoplasma pneumoniae-induced injury via inhibition of Caspase-1/GSDMD-dependent pyroptosis

In conclusion, PD suppressed pulmonary injury triggered by MP infection, by inhibiting the caspase-1/GSDMD-mediated epithelial pyroptosis signaling pathway. Thus, PD may be regarded as a potential therapy for MP-induced inflammation.PMID:37776814 | DOI:10.1016/j.ijmm.2023.151586

Source: International Journal of Medical Microbiology - September 30, 2023 Category: Microbiology Authors: Yiliu Chen Yonghong Jiang Xiuxiu Liu Xiufeng Chen Qiuyue Fan Zhen Xiao Source Type: research