Carbon chain length of perfluoroalkylated carboxylic acids determines inhibitory strength on gonadal 3 β-hydroxysteroid dehydrogenases in humans, rats, and mice

In conclusion, the carbon chain length determines the inhibitory strength of PFCAs on human, rat, and mouse gonadal 3β-HSDs, and the inhibitory strength of PFCAs against human and rat 3β-HSD enzymes shows V-shaped turn.PMID:37871704 | DOI:10.1016/j.toxlet.2023.10.011

Source: Toxicology Letters - October 23, 2023 Category: Toxicology Authors: Huina Zhang Shaowei Wang Ya Chen Jingjing Li Yingna Zhai Yunbing Tang Huitao Li Jianmin Sang Hong Wang Jieqiang Lv Ren-Shan Ge Source Type: research