HnRNPR strongly represses splicing of a critical exon associated with spinal muscular atrophy through binding to an exonic AU-rich element

Conclusion We identified a novel mechanism that contributes to mis-splicing of SMN2 exon 7.

http://jmg.bmj.com/cgi/content/short/60/11/1105?rss=1

Source: Journal of Medical Genetics - October 24, 2023 Category: Genetics & Stem Cells Authors: Jiang, T., Qu, R., Liu, X., Hou, Y., Wang, L., Hua, Y. Tags: Neurogenetics Source Type: research