Deletion of CD47 from Schwann cells and macrophages hastens myelin disruption/dismantling and scavenging in Schwann cells and augments myelin debris phagocytosis in macrophages

Myelin that surrounds axons breaks in trauma and disease; e.g., peripheral nerve and spinal cord injuries (PNI and SCI) and multiple sclerosis (MS). Resulting myelin debris hinders repair if not effectively sc...

Source: Journal of Neuroinflammation - October 23, 2023 Category: Neurology Authors: Miri Gitik, Gerard Elberg, Fanny Reichert, Michael Tal and Shlomo Rotshenker Tags: Research Source Type: research