Interleukin-6 mediates enhanced thrombus development in cerebral arterioles following a brief period of focal brain ischemia.

CONCLUSIONS: The increased vulnerability of the cerebral vasculature to thrombus development after MCAo/R is mediated by IL-6, which is likely derived from brain cells rather than circulating blood cells. These findings suggest that anti-IL-6 therapy may reduce the likelihood of cerebral thrombus development after a transient ischemic attack. PMID: 26054883 [PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/26054883?dopt=Abstract

Source: Experimental Neurology - June 5, 2015 Category: Neurology Authors: Tang YH, Vital S, Russell J, Seifert H, Neil Granger D Tags: Exp Neurol Source Type: research

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