Expression of interleukin-1 β and its receptor in human granulosa cells and their association with steroidogenesis

In conclusion, IL-1β and sIL-1R2 are expressed in human GCs and substantially contribute to ovarian steroidogenesis, suggesting that the IL-1β system may be a potential target for optimizing ovarian hyperstimulation and steroidogenesis in IVF cycles.PMID:37820554 | DOI:10.1016/j.tice.2023.102230

Source: Tissue and Cell - October 11, 2023 Category: Cytology Authors: Amir Fattahi Reza Zarezadeh Yeganeh Rastgar Rezaei Liselotte Mettler Mohammad Nouri Andreas G Schmutzler Ali Salmassi Source Type: research