Insulin-degrading enzyme (IDE) as a modulator of microglial phenotypes in the context of Alzheimer ’s disease and brain aging

The insulin-degrading enzyme (IDE) is an evolutionarily conserved zinc-dependent metallopeptidase highly expressed in the brain, where its specific functions remain poorly understood. Besides insulin, IDE is a...

Source: Journal of Neuroinflammation - October 11, 2023 Category: Neurology Authors: Miriam Corraliza-Gomez, Teresa Bermejo, Jingtao Lilue, Noelia Rodriguez-Iglesias, Jorge Valero, Irene Cozar-Castellano, Eduardo Arranz, Diego Sanchez and Maria Dolores Ganfornina Tags: Research Source Type: research