Predictors of persistent disease in biologic treated type 2 diffuse/eosinophilic chronic rhinosinusitis undergoing surgery

ConclusionLow tissue eosinophils and increased serum neutrophils while on biologics predict for poor response in the biological treatment of with CRSwNP. A serum neutrophil level of ≥5.75 × 109 cells/L predicts for poor response to current biologic therapy.

Source: International Forum of Allergy and Rhinology - October 8, 2023 Category: Allergy & Immunology Authors: Lu Hui Png, Larry Kalish, Raewyn G. Campbell, Kachorn Seresirikachorn, Tobias Albrecht, Nelufer Raji, Christine Choy, Janet Rimmer, Peter Earls, Raymond Sacks, Richard J. Harvey Tags: ORIGINAL ARTICLE Source Type: research