P333 Clinical, pathological heterogeneity and mitochondrial dysfunction in patients with anti-mitochondrial antibodies related myositis

Inflammatory myopathies are a heterogeneous group of rare, acquired autoimmune diseases involving skeletal muscle and other organs and/or tissue. Myositis specific or associated antibodies are commonly correlated with distinct clinical phenotypes of inflammatory myopathies and have helped to refine the classification. Anti-mitochondrial antibodies (AMAs), the hallmark of primary biliary cirrhosis, have been reported in patients with inflammatory myopathies. We aimed to reveal the clinical and histopathological characteristics and explore the mitochondrial dysfunction in patients with AMAs related myopathies.

Source: Neuromuscular Disorders - October 1, 2023 Category: Neurology Authors: W. Zhang, Y. Wang, Y. Zhao, Y. Yuan Source Type: research