Identifying potential immuno-oncology targets in salivary gland mucoepidermoid carcinoma based on inflammatory status and treatment response

CONCLUSION: This preliminary report unveils the importance of assessing immune leukocyte cellular fractions and pathways for future prognostic biomarker discoveries in mucoepidermoid carcinoma as per the involvement of CD45-driven inflammatory and immune mediators in high grade mucoepidermoid carcinoma in non-responders to treatment. These findings will potentially contribute to the development of novel personalised immunotherapies.PMID:37756121 | DOI:10.1111/jop.13488

Source: Methods of Information in Medicine - September 27, 2023 Category: Information Technology Authors: Santhosh Kumar J Urumarudappa Vy Ngoc Thuy Tran Hay Mar Oo Monthira Suntiparpluacha Somponnat Sampattavanich Vinicius Rosa Komkrit Ruangritchankul Joao N Ferreira Risa Chaisuparat Source Type: research