Regulatory architecture of cell identity genes and housekeeping genes

Trends Cell Biol. 2023 Sep 27:S0962-8924(23)00178-2. doi: 10.1016/j.tcb.2023.08.007. Online ahead of print.ABSTRACTGene regulation and chromosome architecture are intimately linked. Genes with prominent roles in cell identity are often regulated by clusters of enhancer elements. By contrast, a recent study shows housekeeping genes are often regulated through clustering of promoters. We discuss here new regulatory insights for these two types of genes.PMID:37775397 | DOI:10.1016/j.tcb.2023.08.007

Source: Trends in Cell Biology - September 29, 2023 Category: Cytology Authors: Alessandra Dall'Agnese Richard Young Source Type: research