Global and endothelial G-protein coupled receptor 75 (GPR75) knockout relaxes pulmonary artery and mitigates hypoxia-induced pulmonary hypertension

CONCLUSION: These results suggest GPR75 has a significant role in the development of hypoxia-induced PH.PMID:37742819 | DOI:10.1016/j.vph.2023.107235

Source: Vascular Pharmacology - September 24, 2023 Category: Drugs & Pharmacology Authors: Catherine A D'Addario Shun Matsumura Atsushi Kitagawa Gregg M Lainer Frank Zhang Melinee D'silva Mohammad Y Khan Ghezal Froogh Artiom Gruzdev Darryl C Zeldin Michal L Schwartzman Sachin A Gupte Source Type: research