Long-Term Efficacy of Dupilumab for Eosinophilic Chronic Rhinosinusitis

CONCLUSION: The NPS remained improved, and the CT score showed further improvement with long-term treatment, whereas olfactory function and olfactory cleft opacification showed significant improvement only after long-term treatment. There was a dissociation between the time to improve in the NPS and CT scores and the time to improve in olfactory function and olfactory cleft opacification. Based on these results, dupilumab should be administered for longer than 1 year, especially for olfactory function.PMID:37750177 | DOI:10.1177/19458924231204128
Source: American Journal of Rhinology and Allergy - Category: ENT & OMF Authors: Source Type: research