Genomic DNA activates the AIM2 inflammasome and STING pathways to induce inflammation in lacrimal gland myoepithelial cells
CONCLUSION: Self-gDNA induces a proinflammatory response in lacrimal gland MECs by activating both the AIM2 inflammasome and STING and thus may contribute to the pathogenesis of pSS.PMID:37769964 | DOI:10.1016/j.jtos.2023.09.012
Source: The Ocular Surface - Category: Opthalmology Authors: Menglu Yang Vanessa Delcroix Anton Lennikov Nicholas Wang Helen P Makarenkova Darlene A Dartt Source Type: research
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