S-layer is a key element in metabolic response and entry into the stationary phase in Bacillus cereus AH187

In this study, we used high-throughput proteomics to investigate how S-layer synthesis affects the allocation of cellular resources in the emetic B. cereus strain AH187. Our results demonstrate that the synthesis of the S-layer plays a crucial role in the pathogen's ability to thrive under stationary growth phase conditions by modulating the stress response, thereby promoting its lifestyle as an emetic pathogen. We conclude that the synthesis of the S-layer is a critical adaptation for emetic B. cereus to successfully colonize specific niches.PMID:37730087 | DOI:10.1016/j.jprot.2023.105007
Source: Journal of Proteomics - Category: Biochemistry Authors: Source Type: research