Voluntary wheel running during adolescence prevents the increase in ethanol intake induced by social defeat in male mice

ConclusionsThe pre-exposure of VWR prevented the increase in consumption and motivation for ethanol induced by SD in susceptible mice. On the other hand, it appears that VWR did not exhibit any significant long-term effects on BDNF signaling, which is mainly affected in susceptible mice after ethanol intake.
Source: Psychopharmacology - Category: Psychiatry Source Type: research