Endocrine disruptors in Adansonia digitata (Linn) extract induce alteration of female Wistar rats' oestrous cycle, hormone and lipid profiles

CONCLUSION: AAMF fraction of A. digitata (L) root bark disrupts the endocrine activity in female Wistar rats. The oleic acid component of the AAMF fraction may be responsible for modulating the activities of reproductive hormones. The authors recommend further studies to ascertain the significance of Adansonia digitata extract's oleic acid in regulating the female reproductive cycle.PMID:37722461 | DOI:10.1016/j.ygcen.2023.114385

Source: General and Comparative Endocrinology - September 18, 2023 Category: Endocrinology Authors: Chibuogwu Ijeoma Chika Nwannenna Agnes Ifeyinwa Ogwu David Garba Magaji Ubah Simon Azubuike Ajayi Itopa Etudaye Source Type: research