Cytotoxicity of WT1-reactive T cells against Wilms tumor: An implication for antigen-specific adoptive immunotherapy

CONCLUSION: WT1-reactive T cells can be effectively enriched from the PBMCs of patients with Wilms tumor. Ex vivo generated WT1-reactive T cells might be considered an adoptive immunotherapeutic option for WT1+ Wilms tumors.PMID:37736339 | PMC:PMC10509739 | DOI:10.34172/bi.2023.27576

Source: Cancer Control - September 22, 2023 Category: Cancer & Oncology Authors: Seyed Mostafa Monzavi Amir Ali Hamidieh Mohammad Vasei Jafar Ai Naser Ahmadbeigi Hamid Arshadi Samad Muhammadnejad Abdol-Mohammad Kajbafzadeh Source Type: research