Butylphthalide improves brain damage induced by renal ischemia-reperfusion injury rats through Nrf2/HO-1 and NOD2/MAPK/NF- κB pathways

This study demonstrates that NBP maintains BBB function by activating the Nrf2/HO-1 pathway and inhibiting the NOD2/MAPK/NF-κB pathway to suppress inflammation and oxidative stress, thereby alleviating renal I/R-induced brain injury.PMID:37732403 | DOI:10.1080/0886022X.2023.2259234

Source: Renal Failure - September 21, 2023 Category: Urology & Nephrology Authors: Jingjing Min Qi Chen Mengxiong Pan Tan Liu Qun Gu Dongwei Zhang Ru Sun Source Type: research