Enhancing near-infrared fluorescence intensity and stability of PLGA-b-PEG micelles by introducing Gd-DOTA at the core boundary

In conclusion, we found that overall fluorescence and stability are improved by introducing Gd-DOTA at the boundary of the PLGA core and PEG shell. Improving micelle stability is crucial for further biomedical applications of micellar probes such as bimodal fluorescence and magnetic resonance imaging.PMID:37732480 | DOI:10.1002/jbm.b.35327

Source: Biomed Res - September 21, 2023 Category: Research Authors: Thi Kim Dung Doan Masakazu Umezawa Kyohei Okubo Masao Kamimura Kohei Soga Source Type: research