Plant bioactive peptides for cardiovascular disease prevention

Adv Food Nutr Res. 2023;106:219-239. doi: 10.1016/bs.afnr.2023.03.005. Epub 2023 Aug 18.ABSTRACTCardiovascular disease (CVD) is a major cause of deaths in industrialized countries and a constantly growing cause of morbidity and mortality worldwide Hypercholesterolemia is one of the main risk factors for CVD progression that may be prevented by lifestyle changes, including diet. This chapter will discuss the role of peptides from plants (soybean, lupin, cowpea, hempseed, and rice bran) sources with pleotropic activity for the prevention of CVD. Overall, the bioactivity that will be mainly discussed it is the hypocholesterolemic one. The very diversified structures of the hypocholesterolemic peptides so far identified explains the reason why they exert their activity through different mechanisms of action that will be extensively described in this review. Doubtlessly, their potential use in nutritional application is desirable, however, only few of them have been tested in vivo. Therefore, more efforts need to be pursued for singling out good candidates for the development of functional foods or dietary supplements.PMID:37722773 | DOI:10.1016/bs.afnr.2023.03.005
Source: Advances in Food and Nutrition Research - Category: Nutrition Authors: Source Type: research