Neutralizing antidrug antibody to emicizumab in patients with severe hemophilia A: Case report of a first noninhibitor patient and review of the literature

CONCLUSION: Although emicizumab is very effective and has minimal immunogenicity, ADAs, albeit rare, can still occur. There have been 4 previously published anti-emicizumab ADA cases with severe HA with inhibitors, and herein, we describe 1 new case with severe HA without inhibitors.PMID:37732158 | PMC:PMC10507376 | DOI:10.1016/j.rpth.2023.102194
Source: Thrombosis and Haemostasis - Category: Hematology Authors: Source Type: research