CDC42-mediated Wnt signaling facilitates odontogenic differentiation of DPCs during tooth root elongation

CONCLUSIONS: We innovatively revealed that CDC42 was responsible for guiding root elongation in a mesenchyme-specific manner. Furthermore, CDC42-mediated canonical Wnt signaling regulated odontogenic differentiation of DPCs during root formation.PMID:37726858 | PMC:PMC10510226 | DOI:10.1186/s13287-023-03486-2

Source: Cell Research - September 19, 2023 Category: Cytology Authors: Tao Zhou Guoqing Chen Yuchan Xu Shuning Zhang Huilin Tang Tao Qiu Weihua Guo Source Type: research