Tissue Expressions of Regulatory Enzymes of the Krebs Cycle in Low- and High-grade Gliomas

CONCLUSION: Regulatory enzymes of the Krebs cycle are increased in high-grade gliomas compared to low-grade gliomas. Glutaminolysis enzymes, namely glutamate dehydrogenase and glutaminase, which are required for resupplying the Krebs cycle, are also increased in order to meet the high energy demand in high-grade gliomas.PMID:37715603 | DOI:10.5137/1019-5149.JTN.40697-22.2

Source: Turkish Neurosurgery - September 16, 2023 Category: Neurosurgery Authors: Burak Tahmazoglu Rahsan Kemerdere Mehmet Edip Akyol Bagnu Orhan Merve Ince Huriye Serin Berrin Bercik Inal Tibet Kacira Taner Tanriverdi Source Type: research