Comparison of three DREADD agonists acting on Gq-DREADDs in the ventral tegmental area to alter locomotor activity in tyrosine hydroxylase:Cre male and female rats

CONCLUSIONS: Large individual variability was observed in both DREADD agonist behavioral effects and receptor expression. These results suggest further basic research would facilitate the utility of these chemogenetic tools for behavioral neuroscience research.PMID:37722510 | DOI:10.1016/j.bbr.2023.114674

Source: Behavioural Brain Research - September 18, 2023 Category: Neurology Authors: Hannah L Robinson Katherine L Nicholson Keith L Shelton Peter J Hamilton Matthew L Banks Source Type: research