Tenofovir diphosphate in dried blood spots and HIV-1 resistance in South Africa

CONCLUSION: TFV-DP in DBS showed a step-wise inverse relationship with VB and drug resistance, with evidence of low cumulative ART adherence in PWH who developed antiretroviral resistance. Monitoring TFV-DP concentrations could be a valuable tool for predicting future VB and future resistance.PMID:37705102 | PMC:PMC10500931 | DOI:10.1186/s12981-023-00552-w

Source: AIDS Research and Therapy - September 13, 2023 Category: Infectious Diseases Authors: Y Singh J Castillo-Mancilla R Madimabe L Jennings C M Ferraris R N Robbins P L Anderson R H Remien C Orrell Source Type: research