The first case of hemorrhagic shock and encephalopathy syndrome with fulminant hypercytokinemia associated with pediatric COVID-19

Infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can lead not only to respiratory symptoms but also to neurologic symptoms with various levels of severity. After the worldwide prevalence of Omicron variant, severe neurological manifestations of coronavirus disease 2019 (COVID-19) such as febrile seizure, demyelinating disease, and cerebrovascular disease, have been reported. However, reports of acute encephalopathy in patients with COVID-19 are quite limited. Especially in terms of cytokine storm-inducing hemorrhagic shock and encephalopathy syndrome (HSES), there is no case reported related to COVID-19.

Source: Brain and Development - September 18, 2023 Category: Neurology Authors: Koyuru Kurane, Keizo Wakae, Hirokazu Yamagishi, Yuta Kawahara, Marika Ono, Daisuke Tamura, Kaito Furuya, Naoyuki Taga, Mitsuru Matsuki, Takanori Yamagata, Kazuhiro Muramatsu Tags: Case Report Source Type: research