Plasma Cetuximab Concentrations Correlate With Survival in Patients With Advanced KRAS Wild Type Colorectal Cancer

CONCLUSION: The standard cetuximab dosing regimen may not be optimal for all patients. Further pharmacokinetic studies are needed to optimize cetuximab dosing given the potential improvement in OS.PMID:37704538 | DOI:10.1016/j.clcc.2023.08.006

Source: Clinical Colorectal Cancer - September 13, 2023 Category: Cancer & Oncology Authors: Di Maria Jiang Shruti Parshad Luna Zhan Hao-Wen Sim Lillian L Siu Geoffrey Liu Jeremy D Shapiro Timothy J Price Derek J Jonker Christos S Karapetis Andrew H Strickland Wenjiang Zhang Mark Jeffery Dongsheng Tu Siobhan Ng Sabe Sabesan Jenny Shannon Amanda T Source Type: research